Flash nanocomplexation
WebScalable production of core–shell nanoparticles by flash nanocomplexation to enhance mucosal transport for oral delivery of insulin. Nanoscale 10, no. 7 (2024): 3307-3319. 第一作者 IF: 7.79 JCR 1 区 & 中科院 1 区 TOP 期刊. 2024 年. 30. WebHere we adopt a kinetically controlled mixing process, termed flash nanocomplexation (FNC), that accelerates the mixing of pDNA solution with polycation lPEI solution to match the PEC assembly kinetics through turbulent mixing in a microchamber. This achieves explicit control of the kinetic conditions for pDNA/lPEI nanoparticle assembly, as ...
Flash nanocomplexation
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WebFlash nanocomplexation as a scalable production method for therapeutic pdna/lpei nanoparticles. In Society for Biomaterials Annual Meeting and Exposition 2024: The … WebWe have invented a new flash nanocomplexation (FNC) process for scalable production of polyelectrolyte complex nanoparticles (US patent issued in 2024); and applied this method to kinetically control the …
WebApr 25, 2024 · Here, we applied the flash nanocomplexation (FNC) method to prepare nanovaccines via polyelectrolyte complexation of chitosan and heparin to coencapsulate the VP1 protein antigen from enterovirus 71, which causes hand–foot–mouth disease (HFMD), with tumor necrosis factor α (TNF) or CpG as adjuvants. Webnovel NP fabrication method termed flash nanocomplexation (FNC) has been recently developed in our lab, which adopts a designed Multi-Inlet Vortex Mixer (MIVM) device …
WebHerein, we report a coordination-driven flash nanocomplexation (cFNC) process to achieve scalable fabrication of doxorubicin-based metal–phenolic nanoparticles (DITH) … WebThe hydrophilic L-DOPA was successfully encapsulated into nanoparticles of tannic acid (TA)/polyvinyl alcohol (PVA) via hydrogen bonding using the flash nanocomplexation (FNC) process, resulting in a high L-DOPA-loading capacity and uniform size in a …
WebDec 7, 2024 · Created polymeric nanoparticles and lipid nanoparticles for the purpose of gene editing using flash nanocomplexation Transfected …
WebThe method involves the complex coacervation of negatively charged DNA plasmid and positive charged lPEI under rapid, highly dynamic, and homogeneous mixing conditions, … the sleep cornerWebMay 24, 2024 · One of the most important trends in developments in electrospinning is to combine itself with traditional materials production and transformation methods to take advantage of the unique properties of nanofibers. In this research, the single-fluid blending electrospinning process was combined with the casting film method to fabricate a … myopathie welanderWebNov 5, 2024 · Here, we applied a scalable and controllable flash nanocomplexation technology to prepare nanoparticulate CpG adjuvant (npCpG), CpG encapsulated in a physical cross-linking network of … the sleep cottageWebHere we report a single-step flash nanocomplexation (FNC) process using turbulent mixing to prepare uniform lipo-complex or lipo-polyplex LNPs in a scalable manner, demonstrating excellent... the sleep cycle consists of distinct stagesWebDec 16, 2024 · A flash nanocomplexation (FNC) process was adopted to confer homogeneous mixing of the three components and control the assembly kinetics, thus enabling efficient encapsulation, a tunable drug release profile, improved nanoparticle size uniformity, and a high degree of colloidal stability. Upon a single intraperitoneal (i.p.) … myopathie unter statinenWebDec 7, 2016 · A flash nanocomplexation method is developed to prepare linear polyethyleneimine/plasmid DNA nanoparticles with narrow size distribution and tunable size and shape under continuous flow operation. … the sleep debt is the result of quizletWebNov 1, 2024 · We highlight the fields of flash nanocomplexation (FNC) and flash nanoprecipitation (FNP), with an emphasis on biomedical applications of FNC, and discuss challenges and future directions for... myopathieen