Phosphonoformate
WebFoscarnet (Foscavir), or phosphonoformic acid (PFA), is an inorganic pyrophosphate analogue that inhibits all known human herpesviruses, including most ganciclovir-resistant CMV isolates and acyclovir-resistant HSV and VZV strains (see Table 295.4 ). 284 Foscarnet also is active against HIV. Foscarnet (phosphonomethanoic acid), known by its brand name Foscavir, is an antiviral medication which is primarily used to treat viral infections involving the Herpesviridae family. It is classified as a pyrophosphate analog DNA polymerase inhibitor. Foscarnet is the conjugate base of a chemical compound with the formula HO2CPO3H2 (Trisodium phosphonoformate).
Phosphonoformate
Did you know?
WebThese are: phosphite of acycloguanosine (P-ACG), Ara-A, cidofovir (CDV), ribavirin (Rib), phosphonoformate (PFA), glycyrrhizic acid (GLN) and alpha-interferon (alpha-IFN). All studied double combinations and triple combinations including P-ACV inhibited replication of both HSV strains more effectively than any drug alone. Web10.1128/AAC.44.1.30-38.2000. Antimicrob. Agents Chemother.€2000, 44(1):30. DOI: Julianna Juhász and Michel G. Bergeron Jocelyne Piret, André Désormeaux ...
WebPhone：0086-13720134139 0086-15971444841. Signaling Pathways. Angiogenesis/Protein Tyrosine Kinase Angiogenesis/Protein Tyrosine Kinase WebSodium Phosphonoformate Tribasic Hexahydrate is one of numerous organosodium compounds manufactured by American Elements under the trade name AE …
WebTriethyl phosphonoformate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS. CoA. CAS #: 1474-78-8 EC Number: 216-016-8 Molar Mass: 210.17 g/mol Hill Formula: C₇H₁₅O₅P. 843410. Web中文别名: 二乙氧基膦酰基甲酸乙酯;甲膦酸三乙酯;膦甲酸三乙酯: 英文别名: Ethyl Diethoxyphosphinylformate(cas:1474-78-8);Diethoxyphosphinylformic Acid Ethyl Ester/(Ethoxycarbonyl)phosphonic Acid Diethyl Ester/Triethyl Phosphonoformate
WebSep 30, 1990 · Introduction Foscarnet (trisodium phosphonoformate) is an antiviral agent with in vitro activity against all known human herpesvirus and some retrovirus including human immunodeficiency virus (HIV) (Sandstrom …
WebJun 29, 1985 · Phosphonoformate, an inhibitor of reverse transcriptase in a number of retroviruses, was shown to have a dose-related inhibitory effect on human T-cell lymphotropic virus type III (HTLV-III) replication in the H9 cell line in vitro. HTLV-III replication was eliminated at a concentration of 680 mumol … helicopter captured ‘floating on airWebPhosphonoformate and Phosphonoacetate are both pretty good mimics of the phosphate group: the 3-dimensional crystal structure is strikingly similar and the charge density distribution is similar. The carboxylic acid functional group of PFA and PAA is effective at hydrogen bonding in both the protonated and charged forms. helicopter cargo netsWebDec 1, 1998 · Foscarnet (trisodium phosphonoformate)is an antiviral agent that has activity against herpesviruses,including cytomegalovirus (CMV),Epstein-Barr virus, herpes simplex virus (HSV) types 1 and 2, and varicella zoster virus (VZV). It also has activity against human immunodeficiency virus (HIV) and hepatitis B virus (HBV). lake drive lumber terrace bcWebthe antiviral compound phosphonoformate (K. i) 0.4 ( 0.1. í. M, K. d. ˇ 0.2. í. M), are shown to be inhibitors of FosA. The crystal structure of FosA from P. aeruginosa with phosphonoformate bound in the active with the Mn(II) center with a geometry similar to that proposed for the transition state of the reaction. helicopter cargo nets uk onlyWebFeb 8, 2024 · Foscarnet (trisodium phosphonoformate) is a pyrophosphate analog. It binds reversibly near the pyrophosphate-binding site of DNA polymerase (or reverse transcriptase) without requiring further modification [ 1 ]. lake drownings in texasWebTriethyl phosphonoformate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA CAS #: 1474-78-8 EC Number: 216-016-8 Molar Mass: 210.17 g/mol Hill Formula: C₇H₁₅O₅P 843410 View Pricing & Availability Recommended Products Overview Supporting Documentation Related Product … helicopter carrier 69helicopter carriers in service