WebMar 30, 2024 · Pindolol Breastfeeding Warnings Limited information indicates that this drug is excreted in low levels in maternal milk. It has a short half-life and only moderate renal excretion, so it would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. Pindolol, a synthetic beta-adrenergic receptor blocking agent with intrinsic sympathomimetic activity is 1-(Indol-4-yloxy)-3 … See more Pindolol is a nonselective beta-adrenergic antagonist (beta-blocker) which possesses intrinsic sympathomimetic activity (ISA) in … See more Pindolol is rapidly and reproducibly absorbed (greater than 95%), achieving peak plasma concentrations within 1 hour of drug administration. Pindolol has no significant first-pass … See more In standard pharmacologic tests in man and animals, Pindolol attenuates increases in heart rate, systolic blood pressure, and cardiac output resulting from exercise and isoproterenol administration, thus … See more
Pindolol Oral: Uses, Side Effects, Interactions, Pictures ... - WebMD
WebThe half-life ranges from 2.5 hours to greater than 30 hours. These findings strongly suggest that caution should be exercised in dosage adjustments of pindolol tablets in such patients. The bioavailability of pindolol tablets is not significantly affected by coadministration of food, hydralazine, hydrochlorothiazide or aspirin. WebTwenty-four hours after the dose, the percentage of the maximal heart rate-attenuating effect was highest for nadolol (pharmacokinetic half-life, 15.5 hours), followed by atenolol and then by pindolol (half-life, 5.5 hours). goodyear boynton beach jog road
Pindolol: Package Insert - Drugs.com
WebPindolol is used to treat high blood pressure. Pindolol is in a class of medications called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve blood … WebIn elderly hypertensive patients with normal renal function, the half-life of pindolol is more variable, averaging about 7 hours, but with values as high as 15 hours. In hypertensive … WebThe kinetics of absorption, distribution and excretion of pindolol have been investigated in 17 volunteers after an oral dose or intravenous infusion of 5 mg. The calculated absorption was 92%. The time course of the plasma levels appeared to follow first order kinetics with an apparent half life of 3.6 (oral) and 3.1 (i.v.) hours. goodyear brake coupons 2015