Shld2 antibody
Web21 Mar 2024 · Within the complex, SHLD2 forms a scaffold which interacts with a SHLD3-MAD2L2 subcomplex via its N-terminus, and with SHLD1 via its C-terminus. … WebProstate cancer ranks fifth in cancer-related mortality in men worldwide. DNA damage is implicated in cancer and DNA damage response (DDR) pathways are in place against this to maintain genomic stability. Impaired DDR pathways play a role in prostate carcinogenesis and germline or somatic mutations in DDR genes have been found in both primary and …
Shld2 antibody
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WebLearn more about Addgene materials from user-contributed reports describing AAV and antibody experiments. Sequence Analyzer. Basic analysis for a user-entered sequence; … WebAnti-SHLD2 Antibody Products. Anti-SHLD2 antibodies are offered by a number of suppliers. This target gene encodes the protein 'shieldin complex subunit 2' in humans and may also be known as FAM35A, FAM35A1, RINN2, bA163M19.1, RINN1-REV7-interacting novel NHEJ …
WebSHP-2 (PTPN11) is a ubiquitously expressed, nonreceptor protein tyrosine phosphatase (PTP). It participates in signaling events downstream of receptors for growth factors, … WebForkhead-associated (FHA)-dependent targeting of CCAR2 to DSB sites re-sensitized BRCA1−/−SHLD2−/− cells to PARPi. Taken together, CCAR2 is a functional component of …
WebLow consistency between antibody staining and RNA expression data. WESTERN BLOT i A Western blot analysis is performed on a panel of human tissues and cell lines to evaluate … Web14 Sep 2024 · MAD2L2 (REV7) plays an important role in DNA double-strand break repair. As a member of the shieldin complex, consisting of MAD2L2, SHLD1, SHLD2 and SHLD3, it …
Web(orb583525) SHLD2 antibody Supplier Biorbyt. Host Rabbit Type Primary Clonality Polyclonal Conjugate Unconjugated Target Shieldin complex subunit 2 UniProt Q86V20 - …
Web17 Jun 2024 · Here, we show that Shld2-/- mice have defective class switch recombination (CSR) and that loss of SHLD2 can suppress the embryonic lethality of a Brca1Δ11 … fire sign colours and meaningsWebSHLD2. Form/Appearance. Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Concentration. 0.5 mg/ml. Storage. For short term … fire sign blue circle meaningWebshld2 ID ZDB-GENE-090313-30 Name shieldin complex subunit 2 Symbol shld2 Nomenclature History Previous Names. si:ch211-134m17.9; Type protein_coding_gene ... fire sign cafe tahoe cityWeb7 Apr 2024 · Here we identify a 53BP1 effector complex, shieldin, that includes C20orf196 (also known as SHLD1), FAM35A (SHLD2), CTC-534A2.2 (SHLD3) and REV7. Shieldin … e thots meaningWebSHLD2 OB-folds are required for suppression of RAD51 IR-induced focus formation. a, Quantitation of RAD51 foci 3 h following 10 Gy irradiation in RPE1 BRCA1-KO/SHLD2-KO … etho uhc 8Web26 Oct 2024 · Title: SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice. found FAM35A, a previously unstudied protein with an … etho twitch streamWebSpecificity: FAM35A/B polyclonal antibody (Shieldin complex subunit 2 and OBSOLETE) binds to endogenous Shieldin complex subunit 2 and OBSOLETE at the amino acid region … etho\\u0027s modded minecraft